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7-DHC, the direct precursor to cholesterol in the Kandutsch-Russell branch of cholesterol biosynthesis pathway, accumulates in Smith-Lemli-Opitz syndrome (SLOS) and accelerates proteolysis of HMG-CoA reductase to suppress sterol biosynthesis 11

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Rhonda Patrick: So what I'm getting at is there is overlap, like cold also activates heat shock proteins